Analysis of Association between Interleukin-6 (<i>IL</i>6), Interleukin-13 (<i>IL</i>13) and Tumor Necrosis Factor-Alpha (<i>TNF-alpha</i>) Gene Polymorphisms and Genetic Susceptibility of Rheumatoid Arthritis in Kuwaiti Arab

Association of Tumor Necrosis Factor-alpha and Interleukin-6 Gene Polymorphisms with Preeclampsia

*Corresponding Author: Madhavi Puppala Research Scholar, Department of Human Genetics, Andhra Univeristy, Visakhapatnam, Andhra Pradesh-530003, India. 4744 Association of Tumor Necrosis Factor-alpha and Interleukin-6 Gene Polymorphisms with Preeclampsia Madhavi Puppala1*, V. Lakshmi Kalpana1, Anuradha A1, M. Sushma2, G. Sudhakar1, Sunil Kumar Polipalli3 1Department of Human Genetics, Andhra Uni...

Lack of Association between Interleukin-10 Gene Promoter Polymorphisms with HIV Susceptibility and Progression to AIDS

Background & Objective: Interleukin (IL)-10 is an important anti-inflammatory and immunomodulatory cytokine. Some authors believe that single nucleotide polymorphisms (SNP) in the promoter region of the IL-10 gene have been associated with susceptibility to HIV infection and progression to AIDS, but its role is not clearly defined yet. The present study was undertaken to evaluate the a...

CIRCULATING SOLUBLE TUMOR NECROSIS FACTOR RECEPTORS, INTERLEUKIN-2 RECEPTORS, TUMOR NECROSIS FACTOR a, AND INTERLEUKIN-6 LEVELS IN RHEUMATOID ARTHRITIS

Tumor Necrosis Factor-α and Interleukin-1- β Polymorphisms in Pre-Eclampsia

Background: Pre-eclampsia is the most common critical condition during pregnancy. Plasma concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1-beta (IL-1β) increase in pregnant women with pre-eclampsia, compared to normal pregnant women. Objective: To investigate the polymorphisms of IL-1β (C+3954T), TNF-α (G- 308A), and (G-238A) in preeclemptic women northeastern Iran. Me...

Interleukin-6 and tumor necrosis factor-alpha gene polymorphisms in chronic idiopathic urticaria.

BACKGROUND This study was performed to evaluate association of gene polymorphisms among proinflammatory cytokines and susceptibility to chronic idiopathic urticaria (CIU). METHODS Ninety patients with prolonged urticaria more than 6 weeks were included as case group. Single nucleotide polymorphisms (SNPs) of IL-6 (G/C -174, G/A nt565) and TNF-α (G/A -308, G/A -238) were evaluated, using polym...